We are using DBGL (DOSBoxGameLauncher), which is a frontend for DosBox, to start the game.
  1. Download and install DosBoxGameLauncher for your OS
  2. Download the game archive dust.dbgl.zip without extracting it
  3. Open DosBoxGameLauncher and import the downloaded file dust.dbgl.zip (Profiles -> Import ...)
  4. Select the profile "Dust: A Tale of the Wired West" and hit the "Play" button.